Which side effect of imipramine (Tofranil) would require immediate medical attention?

Imipramine (Tofranil) is a tricyclic antidepressant that can lead to various side effects, one of which is urinary retention. This condition occurs when a person is unable to completely empty their bladder, which can lead to discomfort and further complications such as urinary tract infections or bladder damage if not addressed promptly.

Urinary retention requiring immediate medical attention is critical because it may signify a worsening condition or serious reaction to the medication. In contrast, the other options – dry mouth, weight gain, and increased appetite – are more common and generally manageable side effects that do not require urgent intervention. While these effects can be uncomfortable or undesirable, they are not life-threatening and typically do not necessitate immediate medical treatment. Recognizing urinary retention as an acute concern highlights the importance of monitoring side effects closely with medications like imipramine.